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All South America Tour & Cruise Packages

Compare 41 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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7 Days
37 Days
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$7,100pp
$99,480pp
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41 Packages (333 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 272
From (per person) 16,956
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 256
From (per person) 14,564
View Trip
15 Day Galapagos & Amazon (Archipel I) with Exodus Adventure Travels
Tour + Cruise

15 Days Quito to Guayaquil
Departures: Jun 2025 to Oct 2025
Trip Styles: Adventure, Small Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 367
From (per person) 17,990
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Antarctica, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$51,660
SUITE
$61,622
Save (per person) 5,499
From (per person) 51,660
View Trip
31 Day Antarctic Voyage with Galápagos and Peru with APT
New ReleaseTour + Cruise

31 Days Guayaquil to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 01 February 2026
Trip Styles: Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos, Peru, Argentina (+1 more), Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$50,856
SUITE
$51,896
Save (per person) 2,839
From (per person) 50,856
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departure: 12 September 2025
Trip Styles: Coach, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$40,052
Save (per person) 2,343
From (per person) 40,052
View Trip
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: May 2025 to Dec 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 228
From (per person) 10,157
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Mar 2025 to Dec 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 495
From (per person) 12,149
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Mar 2026 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,490
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Apr 2025 to Nov 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
13 or 14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 or 14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Feb 2025 to Mar 2026
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Exclusive Savings
From (per person) 12,382
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$27,577
SUITE
$30,151
Save (per person) 6,728
From (per person) 27,577
View Trip
32 Day Antarctica, Argentina & Brazil with Scenic
Tour + Cruise

32 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, South Georgia Island, Falkland Islands (+1 more), Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$50,433
SUITE
$57,408
Save (per person) 13,472
From (per person) 50,433
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Operated By: Globus
Departures: Jul 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save (per person) 552
From (per person) 19,611
View Trip
21 Day South America Revealed with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: May 2025 to Oct 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From (per person) 17,131
View Trip
33 Day Southern Expedition: Antarctica, Peru & the Amazon - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

33 Days Buenos Aires to Cusco
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 08 January 2027
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Argentina, Falkland Islands, South Georgia Island (+1 more), Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$62,943
SUITE
$73,428
Save (per person) 9,577
From (per person) 62,943
View Trip
21 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

21 Days Buenos Aires to Santiago
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Jan 2026 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, Chile
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$52,980
SUITE
$58,177
Save (per person) 5,530
From (per person) 52,980
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Apr 2025 to Sep 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 534
From (per person) 16,139
View Trip
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save (per person) 267
From (per person) 16,316
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$32,558
SUITE
$38,498
Save (per person) 6,787
From (per person) 32,558
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 25,790
View Trip
24 Day Antarctic Voyage with Peru with APT
New ReleaseTour + Cruise

24 Days Lima to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 08 February 2026
Trip Style: Cruise
Countries Visited: Peru, Argentina, Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$30,829
SUITE
$31,869
Save (per person) 2,666
From (per person) 30,829
View Trip
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: May 2025 to Dec 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Mar 2025 to Mar 2026
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save (per person) 269
From (per person) 7,140
View Trip
22 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Nov 2025 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$35,988
SUITE
$41,458
Save (per person) 5,340
From (per person) 35,988
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 14 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$26,460
SUITE
$27,499
Save (per person) 2,635
From (per person) 26,460
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Jul 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 539
From (per person) 17,589
View Trip
11 Day Antarctica: The White Continent with Collette
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Nov 2025 to Mar 2026
Trip Styles: Coach, Small Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
From (per person) 12,050
View Trip
27 Day Wonders of Machu Picchu, the Amazon & Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

27 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse II
Departure: 16 November 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$46,085
SUITE
$51,664
Save (per person) 5,410
From (per person) 46,085
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 559
From (per person) 20,390
View Trip
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