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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 50 unique cruise itineraries from 4 leading cruise lines. April is the most popular month to join a short cruise break sailing in and around the Mediterranean with 75 departures starting between January 2025 and May 2026.
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50 Cruises (75 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Sinfonia
Departures: Apr 2025 to May 2026
Countries Visited: Turkey, Greece, Italy
Exclusive Deal
INSIDE
$481
OCEANVIEW
$560
BALCONY
$738
SUITE
$995
From (per person) 481
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 05 November 2025
Countries Visited: Malta, Spain, France, Italy
Exclusive Deal
INSIDE
$746
OCEANVIEW
$875
BALCONY
$1,004
SUITE
-
From (per person) 746
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Countries Visited: Italy, Spain, France
Early Booking Offer
INSIDE
$994
OCEANVIEW
$1,113
BALCONY
$1,202
SUITE
$1,637
From (per person) 994
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, Spain, France
Early Booking OfferExclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2025
Countries Visited: France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$710
BALCONY
$760
SUITE
-
From (per person) 710
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2025 to Feb 2025
Countries Visited: Italy, Sicily, Tunisia, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$726
SUITE
-
From (per person) 726
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$857
SUITE
-
From (per person) 857
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, France, Italy
Early Booking OfferSave And Sail Offer
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$512
BALCONY
$621
SUITE
$1,017
From (per person) 512
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$393
BALCONY
$492
SUITE
-
From (per person) 393
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 27 April 2026
Countries Visited: France, Italy, Spain
Early Booking Offer
INSIDE
$1,014
OCEANVIEW
$1,133
BALCONY
$1,222
SUITE
$1,657
From (per person) 1,014
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$540
BALCONY
$679
SUITE
$1,471
From (per person) 540
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Italy, Spain
Early Booking OfferExclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,320
From (per person) 608
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 November 2025
Countries Visited: Italy, Spain, France
Early Booking Offer
INSIDE
$510
OCEANVIEW
$619
BALCONY
$659
SUITE
$986
From (per person) 510
View Trip
5 Day Spain & France Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departure: 11 April 2025
Countries Visited: Spain, France
Exclusive Deal
INSIDE
$1,057
OCEANVIEW
$976
BALCONY
$1,007
SUITE
$2,750
Save (per person) 533
From (per person) 976
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 16 April 2025
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
$578
OCEANVIEW
$756
BALCONY
$825
SUITE
$1,350
From (per person) 578
View Trip
4 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departure: 23 October 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$964
OCEANVIEW
$1,115
BALCONY
$1,085
SUITE
$2,202
Save (per person) 544
From (per person) 964
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Bari to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 01 November 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$578
OCEANVIEW
$697
BALCONY
$1,073
SUITE
$1,301
From (per person) 578
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 12 December 2025
Countries Visited: Italy, France
Early Booking Offer
INSIDE
$352
OCEANVIEW
$441
BALCONY
$530
SUITE
$976
From (per person) 352
View Trip
4 Day Northern Europe with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 November 2025
Countries Visited: Spain, France, Italy
Early Booking Offer
INSIDE
$471
OCEANVIEW
$580
BALCONY
$669
SUITE
$996
From (per person) 471
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 03 April 2025
Countries Visited: France, Spain, Italy
Exclusive Deal
INSIDE
$588
OCEANVIEW
$736
BALCONY
$1,132
SUITE
$1,360
From (per person) 588
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Apr 2025 to Dec 2025
Countries Visited: Italy, France
Exclusive DealEarly Booking Offer
INSIDE
$275
OCEANVIEW
$354
BALCONY
$403
SUITE
$839
From (per person) 275
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$384
OCEANVIEW
-
BALCONY
$483
SUITE
$1,257
From (per person) 384
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 May 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$609
OCEANVIEW
$738
BALCONY
$857
SUITE
-
From (per person) 609
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Musica, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Italy
Exclusive DealEarly Booking Offer
INSIDE
$364
OCEANVIEW
$453
BALCONY
$512
SUITE
$839
From (per person) 364
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, Italy, France
Early Booking Offer
INSIDE
$865
OCEANVIEW
$984
BALCONY
$895
SUITE
$1,390
From (per person) 865
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Athens to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 30 October 2025
Countries Visited: Greece, Croatia, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$679
BALCONY
$887
SUITE
$1,065
From (per person) 679
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Marseille to Valencia
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 03 April 2025
Countries Visited: France, Spain
Exclusive Deal
INSIDE
$344
OCEANVIEW
$433
BALCONY
$631
SUITE
$740
From (per person) 344
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Barcelona to La Goulette
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia
Exclusive Deal
INSIDE
$453
OCEANVIEW
-
BALCONY
$611
SUITE
-
From (per person) 453
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 09 May 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$677
OCEANVIEW
$776
BALCONY
$924
SUITE
$1,459
From (per person) 677
View Trip
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